b'INTRODUCTIONIn 2009, funding from the AmericanFIGURE A-2HRS psychosocial content: 2010 and beyondRecovery and Reinvestment Act created the opportunity for the HRS to make its case forWell-being Lifestyle Social Relationshipscreating a genetic resource for research. AwardedLife satisfaction Activities in life Spouse/child/kin/friends multi-year RC2 and RC4 awards (National Institutes of Health Directors OpportunityDomain satisfaction Neighborhood evaluation Positive supportAward), the HRS has genotyped nearly 20,000Depression Religiosity Negative supportparticipants using state-of-the-art technology.Positive/negative affect Discrimination ClosenessWith over 180 approved studies in the National Institutes of Health database of genotypes andHedonic well-being Lifetime traumas Loneliness phenotypes (dbGaP), and participation in dozensPurpose in life Early life experiences Early parental relationshipsof consortia projects, the HRS is now among thePersonal growth Stressful life events Friend contactmost influential genetic cohorts, and by far theFinancial strain Ongoing stress Child contactmost impactful social science survey in the study of human genetics. Personality Work Self-related BeliefsExtraversion Work stress Personal masteryPsychosocial and Lifestyle FactorsCompared to the first 30 years of life, scientistsNeuroticism Work discrimination Perceived constraintsknow relatively little about how we change andOpenness Work satisfaction Hopelessnessgrow in later life. Many people can now expectAgreeableness Capacity to work Subjective ageto live a long life, and to understand more aboutConscientiousness Effort-reward balance Perceptions of agingwhat influences vitality, well-being, and life quality during these added years, the HRS alsoCynical hostility Work supportSubjective social statusmeasures psychosocial functioning. As part ofAnxiety Work/family prioritiesOptimismthe EFTF interview, participants are given aAnger Work/life balance Pessimismself-administered questionnaire that asks about participants well-being, various sources of stress, social relationships, personality and beliefs, and experiences at work (Figure A-2).11'