========================================================================================== Polygenic Scores Note to Users: This codebook is designed to match the distribution dataset. Codebook metadata are derived from the data collection instrument. If you have questions concerning codebook layout or content please bring them to the attention of the HRS staff at hrsquestions@umich.edu. Printing recommendation: Set margins (left/right/top/bottom) to .5 inch; print in portrait orientation using a mono-space 10-point font. ========================================================================================== Section A: POLYGENIC SCORES: AFRICAN ANCESTRY (Respondent) ========================================================================================== HHID HOUSEHOLD IDENTIFIER Section: A Level: Respondent Type: Character Width: 6 Decimals: 0 This variable uniquely identifies an original household across waves. ................................................................................. 3100 000001. Household Identifier Range ========================================================================================== PN PERSON NUMBER Section: A Level: Respondent Type: Character Width: 3 Decimals: 0 Each respondent has a Person Number. The identifier is unique within an original household across waves. ................................................................................. 2068 010. Person number 88 011. Person number 5 012. Person number 1 013. Person number 744 020. Person number 12 021. Person number 78 030. Person number 5 031. Person number 91 040. Person number 8 041. Person number ========================================================================================== PC1_5A AA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 1_5A 2006-2012 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 1_5: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -0.0873 0.0775 0 0.018 0 ------------------------------------------------------------------------------ ========================================================================================== PC1_5B AA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 1_5B 2006-2012 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 1_5: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -0.0701 0.0743 0 0.018 0 ------------------------------------------------------------------------------ ========================================================================================== PC1_5C AA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 1_5C 2006-2012 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 1_5: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -0.0698 0.0761 0 0.018 0 ------------------------------------------------------------------------------ ========================================================================================== PC1_5D AA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 1_5D 2006-2012 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 1_5: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -0.0901 0.0771 0 0.018 0 ------------------------------------------------------------------------------ ========================================================================================== PC1_5E AA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 1_5E 2006-2012 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 1_5: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -0.0728 0.0328 0 0.018 0 ------------------------------------------------------------------------------ ========================================================================================== PC6_10A AA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 6_10 2006-2012 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 6_10: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -0.1003 0.0653 0 0.018 0 ------------------------------------------------------------------------------ ========================================================================================== PC6_10B AA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 6_10 2006-2012 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 6_10: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -0.0702 0.0764 0 0.018 0 ------------------------------------------------------------------------------ ========================================================================================== PC6_10C AA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 6_10 2006-2012 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 6_10: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -0.0661 0.0651 0 0.018 0 ------------------------------------------------------------------------------ ========================================================================================== PC6_10D AA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 6_10 2006-2012 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 6_10: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -0.0704 0.0665 0 0.018 0 ------------------------------------------------------------------------------ ========================================================================================== PC6_10E AA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 6_10 2006-2012 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 6_10: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -0.0704 0.0712 0 0.018 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_GENCOG_CHRG15 AA GENERAL COGNITION PGS (CHARGE 2015 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: General Cognition Polygenic Score, created from CHARGE consortium, 2015 User note: See Documentation Report Section J ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.7554 3.9268 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_BMI_GIANT15 AA BODY MASS INDEX (BMI) PGS (GIANT 2015) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Body Mass Index (BMI) Polygenic Score, created from Genetic Investigation of ANthropometric Traits (GIANT) consortium, 2015 User note: See Documentation Report Section F ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -5.108 3.0254 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_HEIGHT_GIANT14 AA HEIGHT PGS (GIANT 2014) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Height Polygenic Score, created from Genetic Investigation of ANthropometric Traits (GIANT) consortium, 2014 User note: See Documentation Report Section E ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -2.2016 4.3132 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_SCZ_PGC14 AA SCHIZOPHRENIA PGS (PGC 2009) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Schizophrenia Polygenic Score (PGC 2009). The PGSs for schizophrenia were created using results from a 2014 GWAS conducted by the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC). User note: See Documentation Report Section K ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.804 2.4939 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_EDU2_SSGAC16 AA EDUCATIONAL ATTAINMENT 2 PGS (SSGAC 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: The educational attainment PGSs were created using results from a 2016 study by the Social Science Genetic Association Consortium (SSGAC). User note: See Documentation Report Section D ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -4.1654 4.0234 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_EVRSMK_TAG10 AA EVER SMOKER PGS (TAG 2010) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Ever smoker Polygenic Score (TAG 2010). The PGSs for schizophrenia were created using results from a 2014 GWAS conducted by the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC). User note: See Documentation Report Section L ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.7667 3.8951 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_AD_IGAP13 AA ALZHEIMER'S DISEASE(AD)PGS(IGAP2013)(W-O APOE STATUS VARIANTS) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Alzheimer's Disease (AD) Polygenic Score (IGAP 2013) (without ApoE status variants, rs7412 and rs429358) User note: See Documentation Report Section I ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -4.8946 2.8379 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_AD2_IGAP13 AA ALZHEIMER'S DISEASE(AD)PGS(IGAP2013)(W APOE STATUS VARIANTS) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Alzheimer's Disease (AD) Polygenic Score (IGAP 2013) (with ApoE status variants, rs7412 and rs429358) User note: See Documentation Report Section I ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -4.8995 2.8321 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_WC_GIANT15 AA WAIST CIRCUMFERENCE PGS (GIANT 2015) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Waist Circumference Polygenic Score, created from Genetic Investigation of ANthropometric Traits (GIANT) consortium, 2015 User note: See Documentation Report Section G ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.6508 3.913 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_WHR_GIANT15 AA WAIST-TO-HIP RATIO (WHR) PGS (GIANT 2015) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Waist-to-Hip ratio (WHR) Polygenic Score, created from Genetic Investigation of ANthropometric Traits (GIANT) consortium, 2015 User note: See Documentation Report Section G ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.3549 3.2864 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_NEURO_SSGAC16 AA NEUROTICISM PGS (SSGAC 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Neuroticism Polygenic Score. The PGSs for neuroticism were created using results from a 2016 auxiliary GWAS conducted by the Social Science Genetic Association Consortium (SSGAC) as part of their subjective wellbeing GWAS. User note: See Documentation Report Section N ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.6585 3.5273 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_WELLB_SSGAC16 AA SUBJECTIVE WELLBEING PGS (SSGAC 2016 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Subjective wellbeing Polygenic Score. The PGSs for subjective wellbeing were created using results from a 2016 GWAS conducted by the Social Science Genetic Association Consortium (SSGAC). User note: See Documentation Report Section M ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.3183 3.9871 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_DPSYMP_SSGAC16 AA DEPRESSIVE SYMPTOMS PGS (SSGAC 2016 Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Depressive symptoms Polygenic Score. The PGSs for depressive symptoms were created using results from a 2016 auxiliary GWAS conducted by the Social Science Genetic Association Consortium (SSGAC) as part of their subjective wellbeing User note: See Documentation Report Section O ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.898 3.3611 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_CAD_CARDIOGR11 AA CORONARY ARTERY DISEASE (CAD) PGS (CARDIOGRAM 2011) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Coronary Artery Disease (CAD) Polygenic Score (CARDIoGRAM 2011). The PGSs for coronary artery disease (CAD) were created using results from a 2011 study conducted by the Coronary ARtery DIsease Genome wide Replication and Meta-analysis (CARDIoGRAM) consortium. User note: See Documentation Report Section R ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.4435 3.4169 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_MI_CARDIOGR15 AA MYOCARDIAL INFARTCION (MI) PGS (CARDIOGRAM 2015) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Myocardial Infarction (MI) Polygenic Score (CARDIoGRAM 2015). The PGSs for myocardial infarction (MI) were created using 2015 results from a subgroup analysis of coronary artery disease (CAD) conducted by the Coronary ARtery DIsease Genome wide Replication and Meta-analysis (CARDIoGRAM) consortium. User note: See Documentation Report Section S ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -4.3607 3.2198 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_CRTSL_CORNET14 AA PLASMA CORTISOL PGS (CORNET 2014) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Plasma Cortisol Polygenic Score (CORNET 2014). The PGSs for plasma corticol were created using results from a 2014 GWAS conducted by the CORtisol NETwork (CORNET). User note: See Documentation Report Section BB ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.6752 3.7973 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_T2D_DIAGRAM12 AA TYPE 2 DIABETES (T2D) PGS (DIAGRAM 2012) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Type 2 diabetes (T2D) Polygenic Score (DIAGRAM 2012). The PGSs for Type II Diabetes (T2D) were created using GWAS meta-analysis results from a 2012 study conducted by the DIAbetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium. User note: See Documentation Report Section T ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -4.1152 2.4539 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_BIP_PGC11 AA BIPOLAR DISORDER (BIP) PGS (PGC 2011) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Bipolar Disorder (BIP) Polygenic Score (PGC 2011). The PGSs for BP were created using results from a 2011 GWAS conducted by the Bipolar Disorder working group of the Psychiatric GWAS Consortium. User note: See Documentation Report Section X ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.5045 3.9835 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_ADHD_PGC17 AA ATTN DEFICIT HYPERACTIVITY DISORDER (ADHD) PGS (PGC 2017) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Attention Deficit Hyperactivity Disorder (ADHD) Polygenic Score (PGC 2017). The PGSs for ADHD were created using results from a 2010 GWAS conducted by the ADHD subgroup of the Psychiatric GWAS Consortium User note: See Documentation Report Section U ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.4973 3.2744 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_ADHD_PGC10 AA ATTN DEFICIT HYPERACTIVITY DISORDER (ADHD) PGS (PGC 2010) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Attention Deficit Hyperactivity Disorder (ADHD) Polygenic Score (PGC 2010). The 2017 ADHD PGSs were created using results from a 2017 BioRxiv preprint from the Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) and Psychiatric Genetics Consortium (PGC) (Demontis et al., 2017). User note: See Documentation Report Section V ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.3094 4.274 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_XDISORDERPGC13 AA MENTAL HEALTH CROSS DISORDER (XDISORDER) (PGC 2013) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Mental health cross disorder (xdisorder) (PGC 2013). The PGSs for Mental Health Cross-Disorder were created using results from a 2013 GWAS conducted by the Cross Disorder working group of the Psychiatric GWAS Consortium User note: See Documentation Report Section Y ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.1213 3.6235 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_MENARCHE_RPG14 AA AGE AT MENARCHE PGS (REPROGEN 2014, N=6894) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Age at menarche Polygenic Score (ReproGen 2014, n=6894). PGSs for age at menarche were created using results from a 2014 study conducted by the Reproductive Genetics (ReproGen) consortium. User note: See Documentation Report Section Z ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 1910 -3.0781 3.5017 -0.0082 0.9973 1190 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_MENOPAUS_RPG15 AA AGE AT MENOPAUSE PGS (REPROGEN 2015, N=6894) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Age at menopause Polygenic Score (ReproGen 2015, n=6894). PGSs for age at menopause were created using results from a 2014 study conducted by the Reproductive Genetics (ReproGen) consortium. User note: See Documentation Report Section AA ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 1910 -3.5649 3.3244 0.0171 0.9978 1190 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_MDD_PGC13 AA MAJOR DEPRESSIVE DISORDER (MDD) PGS (PGC 2013) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Major Depressive Disorder (MDD) Polygenic Score (PGC 2013). The PGSs for MDD were created using results from a 2013 GWAS conducted by the MDD working group of the Psychiatric GWAS Consortium (PGC). User note: See Documentation Report Section CC ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.3135 3.1772 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_CPD_TAG10 AA NUMBER OF CIGARETTES PER DAY PGS (TAG 2010) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Number of cigarettes per day Polygenic Score (TAG 2010). PGSs for smoking quantity, measured as number of cigarettes smoked per day (CPD), were created using results from a 2010 GWAS conducted by the Tobacco and Genetics Consortium (TAG). User note: See Documentation Report Section Q ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.0147 3.9797 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_EXTRAV_GPC17 AA EXTRAVERSION PGS (GPC 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Extraversion Polygenic Score (GPC 2016). The extraversion PGSs were created using results from a 2016 study by the Genetics of Personality Consortium (GPC). User note: See Documentation Report Section DD ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.9771 3.559 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_AUTISM_PGC17 AA AUTISM PGS (PGC 2017) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Autism Polygenic Score (PGC 2017). The PGSs for autism were created using results from a 2017 GWAS conducted by the Autism Spectrum Disorders Working Group of the Psychiatric Genomics Consortium. User note: See Documentation Report Section W ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -2.9999 2.6212 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_LNGVTY_CHARG15 AA LONGEVITY PGS (CHARGE 2015) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Longevity Polygenic Score, created from CHARGE consortium, 2015 User note: See Documentation Report Section P ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.6992 5.2637 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_AB_BROAD17 AA ANTISOCIAL BEHAVIOR PGS (BROAD 2017) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Antisocial behavior Polygenic Score. The antisocial behavior (AB) PGSs were created using results from a 2017 study by the Broad Antisocial Behavior Consortium. User note: See Documentation Report Section EE ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.6501 3.3815 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_EDU3_SSGAC18 AA EDUCATIONAL ATTAINMENT 3 PGS (SSGAC 2018) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Educational Attainment 3 Polygenic Score. The educational attainment PGSs were created using results from a 2018 study by the Social Science Genetic Association Consortium (SSGAC). User note: See Documentation Report Section FF ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.2124 3.4391 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_OCD_IOCDF17 AA OBSESSIVE COMPULSIVE DISORDER (OCD) PGS (IOCDF 2017) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Obsessive Compulsive Disorder (OCD) Polygenic Score (IOCDF 2017). The obsessive-compulsive disorder (OCD) PGSs were created using results from a 2017 study by International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS). User note: See Documentation Report Section GG ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.2128 3.6229 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_AFBC_SOCGEN16 AA AGE AT FIRST BIRTH PGS, COMBINED GWAS (BARBAN 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Age at first birth PGS, combined GWAS (Barban 2016). PGSs for age at first birth (AFB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section HH ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.052 4.3151 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_AFBF_SOCGEN16 AA AGE AT FIRST BIRTH PGS, FEMALE GWAS (BARBAN 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Age at first birth PGS, Female GWAS (Barban 2016). PGSs for age at first birth (AFB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section HH ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.5119 4.6066 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_AFBM_SOCGEN16 AA AGE AT FIRST BIRTH PGS, MALE GWAS (BARBAN 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Age at first birth PGS, Male GWAS (Barban 2016). PGSs for age at first birth (AFB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section HH ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.6245 4.1508 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_NEBC_SOCGEN16 AA NUM CHILDREN EVER BORN PGS, COMBINED GWAS (BARBAN 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Number of children ever born PGS, combined GWAS (Barban 2016). PGSs for number of children ever born (NEB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section II ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.0266 4.2106 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_NEBF_SOCGEN16 AA NUM CHILDREN EVER BORN PGS, FEMALE GWAS (BARBAN 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Number of children ever born PGS, Female GWAS (Barban 2016). PGSs for number of children ever born (NEB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section II ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.2099 4.6814 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_NEBM_SOCGEN16 AA NUM OF CHILDREN EVER BORN PGS, MALE GWAS (BARBAN 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Number of children ever born PGS, Male GWAS (Barban 2016). PGSs for number of children ever born (NEB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section II ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.1419 3.3947 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_MDD2_PGC18 AA MAJOR DEPRESSIVE DISORDER 2 (MDD2) PGS (PGC 2018) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Major Depressive Disorder 2 (MDD2) Polygenic Score. PGSs for major depressive disorder version 2 (MDD2) were created using results from a 2018 study conducted by the Psychiatric Genomics Consortium (PGC). User note: See Documentation Report Section JJ ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -4.3808 2.7037 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_PTSDAA_PGC18 AA POST TRAUMATIC STRESS DISORDER(PTSD)PGS AFRICAN GWAS(PGC 2018) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Post traumatic stress disorder (PTSD) PGS, African GWAS. The PTSD PGSs were created using results from a 2018 study by the Psychiatric Genetics Consortium (Duncan et al., 2018). User note: See Documentation Report Section KK ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -4.3669 3.9766 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_PTSDEA_PGC18 AA POST TRAUMATIC STRESS DISORDER(PTSD)PGS EUROPEAN GWAS(PGC 2018) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Post traumatic stress disorder (PTSD) PGS, European GWAS. The PTSD PGSs were created using results from a 2018 study by the Psychiatric Genetics Consortium (Duncan et al., 2018). User note: See Documentation Report Section KK ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -5.3341 2.3727 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_PTSDC_PGC18 AA POST TRAUMATIC STRESS DISORDER(PTSD)PGS COMBINED GWAS(PGC 2018) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Post traumatic stress disorder (PTSD) PGS, Combined GWAS. The PTSD PGSs were created using results from a 2018 study by the Psychiatric Genetics Consortium (Duncan et al., 2018). User note: See Documentation Report Section KK ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -4.0085 3.0913 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_HDL_GLGC13 AA HIGH DENSITY LIPOPROTEIN (HDL) PGS (GLGC 2013) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: High density lipoprotein (HDL) Polygenic Score. The HDL, LDL, and TC PGS were created using results from a 2013 study by the Global Lipid Genetics Consortium User note: See Documentation Report Section LL ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -2.9571 3.8984 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_LDL_GLGC13 AA LOW DENSITY LIPOPROTEIN (LDL) PGS (GLGC 2013) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Low density lipoprotein (LDL) Polygenic Score. The HDL, LDL, and TC PGS were created using results from a 2013 study by the Global Lipid Genetics Consortium User note: See Documentation Report Section LL ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -4.4534 3.0397 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_TC_GLGC13 AA TOTAL CHOLESTEROL (TC) PGS (GLGC 2013) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Total cholesterol (TC) Polygenic Score. The HDL, LDL, and TC PGS were created using results from a 2013 study by the Global Lipid Genetics Consortium User note: See Documentation Report Section LL ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -5.0095 3.4501 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_ANXFS_ANGST16 AA ANXIETY FACTOR SCORE PGS (ANGST 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Anxiety factor score Polygenic Score. The Anxiety PGSs were created using results from a 2016 study by the Anxiety NeuroGenetics Study (ANGST) Consortium (Otowa et al., 2016). User note: See Documentation Report Section MM ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -4.0489 4.1461 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== AA_PGS3_ANXCC_ANGST16 AA ANXIETY CASE CONTROL PGS (ANGST 2016) Section: A Level: Respondent Type: Numeric Width: 12 Decimals: Best African Ancestry: Anxiety case control Polygenic Score. The Anxiety PGSs were created using results from a 2016 study by the Anxiety NeuroGenetics Study (ANGST) Consortium (Otowa et al., 2016). User note: See Documentation Report Section MM ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 3100 -3.5251 3.3542 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== VERSION VERSION NUMBER Section: A Level: Respondent Type: Numeric Width: 8 Decimals: 0 ................................................................................. 3100 3. October 2018 ========================================================================================== Section E: POLYGENIC SCORES: EUROPEAN ANCESTRY (Respondent) ========================================================================================== HHID HOUSEHOLD IDENTIFIER Section: E Level: Respondent Type: Character Width: 6 Decimals: 0 This variable uniquely identifies an original household across waves. ................................................................................. 12090 000001. Household Identifier Range ========================================================================================== PN PERSON NUMBER Section: E Level: Respondent Type: Character Width: 3 Decimals: 0 Each respondent has a Person Number. The identifier is unique within an original household across waves. ................................................................................. 6315 010. Person number 377 011. Person number 17 012. Person number 013. Person number 4124 020. Person number 119 021. Person number 6 022. Person number 458 030. Person number 29 031. Person number 4 032. Person number 601 040. Person number 38 041. Person number 2 042. Person number ========================================================================================== PC1_5A EA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 1_5A 2006-2012 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 1_5: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -0.0374 0.0498 0 0.0091 0 ------------------------------------------------------------------------------ ========================================================================================== PC1_5B EA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 1_5B 2006-2012 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 1_5: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -0.0562 0.0161 0 0.0091 0 ------------------------------------------------------------------------------ ========================================================================================== PC1_5C EA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 1_5C 2006-2012 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 1_5: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -0.0241 0.0213 0 0.0091 0 ------------------------------------------------------------------------------ ========================================================================================== PC1_5D EA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 1_5D 2006-2012 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 1_5: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -0.0473 0.0339 0 0.0091 0 ------------------------------------------------------------------------------ ========================================================================================== PC1_5E EA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 1_5E 2006-2012 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 1_5: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -0.0463 0.0112 0 0.0091 0 ------------------------------------------------------------------------------ ========================================================================================== PC6_10A EA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 6_10 2006-2012 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 6_10: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -0.0317 0.0348 0 0.0091 0 ------------------------------------------------------------------------------ ========================================================================================== PC6_10B EA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 6_10 2006-2012 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 6_10: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -0.0435 0.0451 0 0.0091 0 ------------------------------------------------------------------------------ ========================================================================================== PC6_10C EA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 6_10 2006-2012 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 6_10: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -0.0342 0.0375 0 0.0091 0 ------------------------------------------------------------------------------ ========================================================================================== PC6_10D EA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 6_10 2006-2012 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 6_10: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -0.0361 0.0346 0 0.0091 0 ------------------------------------------------------------------------------ ========================================================================================== PC6_10E EA ANCESTRY-SPECIFIC PRINCIPAL COMPONENT SET 6_10 2006-2012 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best Ancestry-specific Principal Component Set 6_10: Must use all five PC in set 1-5 or all 10 PCs in set 1-10, SHUFFLED User note: See Documentation Report Section C ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -0.0416 0.0298 0 0.0091 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_GENCOG_CHRG15 EA GENERAL COGNITION PGS (CHARGE 2015) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: General Cognition Polygenic Score, created from CHARGE consortium, 2015 User note: See Documentation Report Section J ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.9566 4.0319 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_BMI_GIANT15 EA BODY MASS INDEX (BMI) PGS (GIANT 2015) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Body Mass Index (BMI) Polygenic Score, created from Genetic Investigation of ANthropometric Traits (GIANT) consortium, 2015 User note: See Documentation Report Section F ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.6358 4.0777 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_HEIGHT_GIANT14 EA HEIGHT PGS (GIANT 2014) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Height Polygenic Score, created from Genetic Investigation of ANthropometric Traits (GIANT) consortium, 2014 User note: See Documentation Report Section E ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.483 3.0284 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_SCZ_PGC14 EA SCHIZOPHRENIA PGS (PGC 2009) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Schizophrenia Polygenic Score (PGC 2009). The PGSs for schizophrenia were created using results from a 2014 GWAS conducted by the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC). User note: See Documentation Report Section K ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.6718 3.415 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_EDU2_SSGAC16 EA EDUCATIONAL ATTAINMENT 2 PGS (SSGAC 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: The educational attainment PGSs were created using results from a 2016 study by the Social Science Genetic Association Consortium (SSGAC). User note: See Documentation Report Section D ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.6882 3.8099 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_EVRSMK_TAG10 EA EVER SMOKER PGS (TAG 2010) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Ever smoker Polygenic Score (TAG 2010). The PGSs for schizophrenia were created using results from a 2014 GWAS conducted by the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC). User note: See Documentation Report Section L ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.684 3.9219 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_AD_IGAP13 EA ALZHEIMER'S DISEASE(AD)PGS(IGAP2013)(W-O APOE STATUS VARIANTS) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Alzheimer's Disease (AD) Polygenic Score (IGAP 2013) (without ApoE status variants, rs7412 and rs429358) User note: See Documentation Report Section I ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.9518 4.0819 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_AD2_IGAP13 EA ALZHEIMER'S DISEASE(AD)PGS(IGAP2013)(W APOE STATUS VARIANTS) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Alzheimer's Disease (AD) Polygenic Score (IGAP 2013) (with ApoE status variants, rs7412 and rs429358) User note: See Documentation Report Section I ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.9533 4.0657 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_WC_GIANT15 EA WAIST CIRCUMFERENCE PGS (GIANT 2015) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Waist Circumference Polygenic Score, created from Genetic Investigation of ANthropometric Traits (GIANT) consortium, 2015 User note: See Documentation Report Section G ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.4722 3.5285 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_WHR_GIANT15 EA WAIST-TO-HIP RATIO (WHR) PGS (GIANT 2015) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Waist-to-Hip ratio (WHR) Polygenic Score, created from Genetic Investigation of ANthropometric Traits (GIANT) consortium, 2015 User note: See Documentation Report Section G ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.8474 3.7781 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_NEURO_SSGAC16 EA NEUROTICISM PGS (SSGAC 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Neuroticism Polygenic Score. The PGSs for neuroticism were created using results from a 2016 auxiliary GWAS conducted by the Social Science Genetic Association Consortium (SSGAC) as part of their subjective wellbeing GWAS. User note: See Documentation Report Section N ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.7088 3.5731 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_WELLB_SSGAC16 EA SUBJECTIVE WELLBEING PGS (SSGAC 2016 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Subjective wellbeing Polygenic Score. The PGSs for subjective wellbeing were created using results from a 2016 GWAS conducted by the Social Science Genetic Association Consortium (SSGAC). User note: See Documentation Report Section M ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.8482 3.6674 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_DPSYMP_SSGAC16 EA DEPRESSIVE SYMPTOMS PGS (SSGAC 2016 Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Depressive symptoms Polygenic Score. The PGSs for depressive symptoms were created using results from a 2016 auxiliary GWAS conducted by the Social Science Genetic Association Consortium (SSGAC) as part of their subjective wellbeing User note: See Documentation Report Section O ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.1314 3.5714 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_CAD_CARDIOGR11 EA CORONARY ARTERY DISEASE (CAD) PGS (CARDIOGRAM 2011) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Coronary Artery Disease (CAD) Polygenic Score (CARDIoGRAM 2011). The PGSs for coronary artery disease (CAD) were created using results from a 2011 study conducted by the Coronary ARtery DIsease Genome wide Replication and Meta-analysis (CARDIoGRAM) consortium. User note: See Documentation Report Section R ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.7154 3.8205 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_MI_CARDIOGR15 EA MYOCARDIAL INFARTCION (MI) PGS (CARDIOGRAM 2015) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Myocardial Infarction (MI) Polygenic Score (CARDIoGRAM 2015). The PGSs for myocardial infarction (MI) were created using 2015 results from a subgroup analysis of coronary artery disease (CAD) conducted by the Coronary ARtery DIsease Genome wide Replication and Meta-analysis (CARDIoGRAM) consortium. User note: See Documentation Report Section S ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.6743 3.6206 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_CRTSL_CORNET14 EA PLASMA CORTISOL PGS (CORNET 2014) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Plasma Cortisol Polygenic Score (CORNET 2014). The PGSs for plasma corticol were created using results from a 2014 GWAS conducted by the CORtisol NETwork (CORNET). User note: See Documentation Report Section BB ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.0307 3.5462 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_T2D_DIAGRAM12 EA TYPE 2 DIABETES (T2D) PGS (DIAGRAM 2012) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Type 2 diabetes (T2D) Polygenic Score (DIAGRAM 2012). The PGSs for Type II Diabetes (T2D) were created using GWAS meta-analysis results from a 2012 study conducted by the DIAbetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium. User note: See Documentation Report Section T ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.2976 4.4832 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_BIP_PGC11 EA BIPOLAR DISORDER (BIP) PGS (PGC 2011) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Bipolar Disorder (BIP) Polygenic Score (PGC 2011). The PGSs for BP were created using results from a 2011 GWAS conducted by the Bipolar Disorder working group of the Psychiatric GWAS Consortium. User note: See Documentation Report Section X ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.7061 3.9466 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_ADHD_PGC17 EA ATTN DEFICIT HYPERACTIVITY DISORDER (ADHD) PGS (PGC 2017) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Attention Deficit Hyperactivity Disorder (ADHD) Polygenic Score (PGC 2017). The PGSs for ADHD were created using results from a 2010 GWAS conducted by the ADHD subgroup of the Psychiatric GWAS Consortium User note: See Documentation Report Section U ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.5703 3.6822 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_ADHD_PGC10 EA ATTN DEFICIT HYPERACTIVITY DISORDER (ADHD) PGS (PGC 2010) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Attention Deficit Hyperactivity Disorder (ADHD) Polygenic Score (PGC 2010). The 2017 ADHD PGSs were created using results from a 2017 BioRxiv preprint from the Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) and Psychiatric Genetics Consortium (PGC) (Demontis et al., 2017). User note: See Documentation Report Section V ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.6181 4.4034 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_XDISORDERPGC13 EA MENTAL HEALTH CROSS DISORDER (XDISORDER) (PGC 2013) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Mental health cross disorder (xdisorder) (PGC 2013). The PGSs for Mental Health Cross-Disorder were created using results from a 2013 GWAS conducted by the Cross Disorder working group of the Psychiatric GWAS Consortium User note: See Documentation Report Section Y ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.2811 3.5207 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_MENARCHE_RPG14 EA AGE AT MENARCHE PGS (REPROGEN 2014, N=6894) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Age at menarche Polygenic Score (ReproGen 2014, n=6894). PGSs for age at menarche were created using results from a 2014 study conducted by the Reproductive Genetics (ReproGen) consortium. User note: See Documentation Report Section Z ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 6894 -3.3547 4.2384 0.0077 0.9994 5196 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_MENOPAUS_RPG15 EA AGE AT MENOPAUSE PGS (REPROGEN 2015, N=6894) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Age at menopause Polygenic Score (ReproGen 2015, n=6894). PGSs for age at menopause were created using results from a 2014 study conducted by the Reproductive Genetics (ReproGen) consortium. User note: See Documentation Report Section AA ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 6894 -3.4417 4.6981 -0.0215 1.0085 5196 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_MDD_PGC13 EA MAJOR DEPRESSIVE DISORDER (MDD) PGS (PGC 2013) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Major Depressive Disorder (MDD) Polygenic Score (PGC 2013). The PGSs for MDD were created using results from a 2013 GWAS conducted by the MDD working group of the Psychiatric GWAS Consortium (PGC). User note: See Documentation Report Section CC ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.4232 4.0641 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_CPD_TAG10 EA NUMBER OF CIGARETTES PER DAY PGS (TAG 2010) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Number of cigarettes per day Polygenic Score (TAG 2010). PGSs for smoking quantity, measured as number of cigarettes smoked per day (CPD), were created using results from a 2010 GWAS conducted by the Tobacco and Genetics Consortium (TAG). User note: See Documentation Report Section Q ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.6388 3.9187 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_EXTRAV_GPC17 EA EXTRAVERSION PGS (GPC 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Extraversion Polygenic Score (GPC 2016). The extraversion PGSs were created using results from a 2016 study by the Genetics of Personality Consortium (GPC). User note: See Documentation Report Section DD ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.644 3.509 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_AUTISM_PGC17 EA AUTISM PGS (PGC 2017) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Autism Polygenic Score (PGC 2017). The PGSs for autism were created using results from a 2017 GWAS conducted by the Autism Spectrum Disorders Working Group of the Psychiatric Genomics Consortium. User note: See Documentation Report Section W ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.5226 3.1146 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_LNGVTY_CHARG15 EA LONGEVITY PGS (CHARGE 2015) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Longevity Polygenic Score, created from CHARGE consortium, 2015 User note: See Documentation Report Section P ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.5044 4.6316 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_AB_BROAD17 EA ANTISOCIAL BEHAVIOR PGS (BROAD 2017) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Antisocial behavior Polygenic Score. The antisocial behavior (AB) PGSs were created using results from a 2017 study by the Broad Antisocial Behavior Consortium. User note: See Documentation Report Section EE ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.5825 4.0424 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_EDU3_SSGAC18 EA EDUCATIONAL ATTAINMENT 3 PGS (SSGAC 2018) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Educational Attainment 3 Polygenic Score. The educational attainment PGSs were created using results from a 2018 study by the Social Science Genetic Association Consortium (SSGAC). User note: See Documentation Report Section FF ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.3819 3.3696 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_OCD_IOCDF17 EA OBSESSIVE COMPULSIVE DISORDER (OCD) PGS (IOCDF 2017) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Obsessive Compulsive Disorder (OCD) Polygenic Score (IOCDF 2017). The obsessive-compulsive disorder (OCD) PGSs were created using results from a 2017 study by International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS). User note: See Documentation Report Section GG ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.9984 3.8309 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_AFBC_SOCGEN16 EA AGE AT FIRST BIRTH PGS, COMBINED GWAS (BARBAN 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Age at first birth PGS, combined GWAS (Barban 2016). PGSs for age at first birth (AFB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section HH ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.6674 4.4296 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_AFBF_SOCGEN16 EA AGE AT FIRST BIRTH PGS, FEMALE GWAS (BARBAN 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Age at first birth PGS, Female GWAS (Barban 2016). PGSs for age at first birth (AFB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section HH ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.8214 4.4299 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_AFBM_SOCGEN16 EA AGE AT FIRST BIRTH PGS, MALE GWAS (BARBAN 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Age at first birth PGS, Male GWAS (Barban 2016). PGSs for age at first birth (AFB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section HH ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.93 3.9128 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_NEBC_SOCGEN16 EA NUM CHILDREN EVER BORN PGS, COMBINED GWAS (BARBAN 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Number of children ever born PGS, combined GWAS (Barban 2016). PGSs for number of children ever born (NEB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section II ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.6532 3.5017 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_NEBF_SOCGEN16 EA NUM CHILDREN EVER BORN PGS, FEMALE GWAS (BARBAN 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Number of children ever born PGS, Female GWAS (Barban 2016). PGSs for number of children ever born (NEB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section II ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -5.1495 4.122 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_NEBM_SOCGEN16 EA NUM OF CHILDREN EVER BORN PGS, MALE GWAS (BARBAN 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Number of children ever born PGS, Male GWAS (Barban 2016). PGSs for number of children ever born (NEB) were created using results from a 2016 study conducted by the Sociogenome consortium. User note: See Documentation Report Section II ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.4955 5.5651 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_MDD2_PGC18 EA MAJOR DEPRESSIVE DISORDER 2 (MDD2) PGS (PGC 2018) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Major Depressive Disorder 2 (MDD2) Polygenic Score. PGSs for major depressive disorder version 2 (MDD2) were created using results from a 2018 study conducted by the Psychiatric Genomics Consortium (PGC). User note: See Documentation Report Section JJ ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.6808 5.5 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_PTSDAA_PGC18 EA POST TRAUMATIC STRESS DISORDER(PTSD)PGS AFRICAN GWAS(PGC2018) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Post traumatic stress disorder (PTSD) PGS, African GWAS. The PTSD PGSs were created using results from a 2018 study by the Psychiatric Genetics Consortium (Duncan et al., 2018). User note: See Documentation Report Section KK ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.2664 4.3849 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_PTSDEA_PGC18 EA POST TRAUMATIC STRESS DISORDER(PTSD)PGS EUROPEAN GWAS(PGC2018) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Post traumatic stress disorder (PTSD) PGS, European GWAS. The PTSD PGSs were created using results from a 2018 study by the Psychiatric Genetics Consortium (Duncan et al., 2018). User note: See Documentation Report Section KK ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -2.9667 9.3142 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_PTSDC_PGC18 EA POST TRAUMATIC STRESS DISORDER(PTSD)PGS COMBINED GWAS(PGC2018) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Post traumatic stress disorder (PTSD) PGS, Combined GWAS. The PTSD PGSs were created using results from a 2018 study by the Psychiatric Genetics Consortium (Duncan et al., 2018). User note: See Documentation Report Section KK ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.6954 3.6772 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_HDL_GLGC13 EA HIGH DENSITY LIPOPROTEIN (HDL) PGS (GLGC 2013) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: High density lipoprotein (HDL) Polygenic Score. The HDL, LDL, and TC PGS were created using results from a 2013 study by the Global Lipid Genetics Consortium User note: See Documentation Report Section LL ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.4686 3.7526 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_LDL_GLGC13 EA LOW DENSITY LIPOPROTEIN (LDL) PGS (GLGC 2013) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Low density lipoprotein (LDL) Polygenic Score. The HDL, LDL, and TC PGS were created using results from a 2013 study by the Global Lipid Genetics Consortium User note: See Documentation Report Section LL ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.9508 3.8786 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_TC_GLGC13 EA TOTAL CHOLESTEROL (TC) PGS (GLGC 2013) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Total cholesterol (TC) Polygenic Score. The HDL, LDL, and TC PGS were created using results from a 2013 study by the Global Lipid Genetics Consortium User note: See Documentation Report Section LL ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.9057 3.591 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_ANXFS_ANGST16 EA ANXIETY FACTOR SCORE PGS (ANGST 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Anxiety factor score Polygenic Score. The Anxiety PGSs were created using results from a 2016 study by the Anxiety NeuroGenetics Study (ANGST) Consortium (Otowa et al., 2016). User note: See Documentation Report Section MM ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -3.8924 3.7785 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== EA_PGS3_ANXCC_ANGST16 EA ANXIETY CASE CONTROL PGS (ANGST 2016) Section: E Level: Respondent Type: Numeric Width: 12 Decimals: Best European Ancestry: Anxiety case control Polygenic Score. The Anxiety PGSs were created using results from a 2016 study by the Anxiety NeuroGenetics Study (ANGST) Consortium (Otowa et al., 2016). User note: See Documentation Report Section MM ................................................................................. ------------------------------------------------------------------------------ N Min Max Mean SD Miss 12090 -4.2859 3.9533 0 1 0 ------------------------------------------------------------------------------ ========================================================================================== VERSION VERSION NUMBER Section: E Level: Respondent Type: Numeric Width: 8 Decimals: 0 ................................................................................. 12090 3. October 2018 ==========================================================================================