Sharon L.R. Kardia

Co-Investigator Picture
Health and Retirement Study

Contact Information

4605 SPH I
1415 Washington Heights
Ann Arbor, Michigan 48109-2029


University of Michigan, Ph.D. Human Genetics, 1991
University of Michigan, M.A. Statistics, 1990
Carnegie-Mellon University, B.S. Biological Sciences, 1985

Research and Projects

Dr. Kardia's main research interests are in the genetic epidemiology of common chronic diseases and their risk factors. She is particularly interested in gene-environment and gene-gene interactions and in developing novel analytical strategies to understand the complex relationship between genetic variation, environmental variation, and risk of common chronic diseases. Her research utilizes genomic, epigenomic, transcriptomic, and proteomic measures on large epidemiological cohorts.

Selected Recent Publications

Christensen, K.D., Roberts, J.S., Zikmund-Fisher, B.J., Kardia, S.L., McBride, C.M., Linnenbringer, E., Green, R.C. REVEAL Study Group.. Associations between self-referral and health behavior responses to genetic risk information. Genome Med, 7(1), 10 [2015]

Platt, J. and Kardia, S.. Public Trust in Health Information Sharon: Implications for Biobanking and Electronic Health Record Systems. J Pers Med, 5(1), 3-21 [2015]

Shetty, P.B., Tang, H., Feng, T., Tayo, B., Morrison, A.C., Kardia, S.L., Hanis, C.L., Arnett, D.K., Hunt, S.C., Boerwinkle, E., Rao, D.C., Cooper, R.S., Risch, N., Zhu, X.. Variants for HDL-C, LDL-C, and Triglycerides Identified from Admixture Mapping and Fine-Mapping Analysis in African American Families. Circ Cardiovasc Genet, 8(1), 106-113 [2015]

Kim, D.S., Smith, J.A., Bielak, L.F., Wu, C.Y., Sun, Y.V., Sheedy, P.F., Turner, S.T., Peyser, P.A., Kardia, S.L.. relationship between diastolic blood pressure and coronary artery calcification is dependent on single nucleotide polymorphisms on chromosome 9p21.3. BMC Med Genet, 15(1), 89 [2014]

Ko, Y.A., Mukherjee, B., Smith, J.A., Park, S.K., Kardia, S.L., Allison, M.A.,Vokonas, P.A., Chen, J., Diez-Roux, A.V.. Testing departure from additivity in Tukey's model using shrinkage: application to a longitudinal setting. Stat Med, 23(29), 5177-5191 [2014]

Liao, L.N., Chen, C.C., Wu, F.Y., Lin, C.C., Hsiao, J.H., Chang, C.T., Kardia, S.L., Li, T.C., Tsai, F.J.. Identified single-nucleotide polymorphisms and haplotypes at 16q22.1 increase diabetic nephropathy risk in Han Chineses population. BMC Genet, 15, 113 [2014]

Lin, C.C., Peyser, P.A., Kardia, S.L., Li, C.I., Liu, C.S., Chu, J.S., Lin, W.Y., Li, T.C. Heritability of cardiovascular risk factors in a Chineses population - Taichung Community Health Study and Family Cohort. Atherosclerosis, 235(2), 488-495 [2014]

Turner, S.T., Kardia, S.L.R., Boerwinkle, E., deAndrade, M. . Multivariate linkage analysis of blood pressure and body mass index . General Epidemiology, 27, 64-73. [2004]

O'Meara, J., Kardia, S.L.R., Armon, J.J., Turner, S.T. . Prevalence, treatment, and control of dyslipidemia in a hypertensive population . Archives of Internal Medicine, 164, 1313-1318. [2004]

Daniels, P.R., Kardia, S.L.R., Hanis, C.L., Brown, C.A., Hutchinson, R., Boerwinkle, E., Sing, C.F., Turner, S.T. . Familial aggregation of hypertension treatment and control . American Journal of Medicine, 116, 676-681. [2004]

Sing, C.F., Stengard, J.H., Kardia, S.L.R. . Genes, environment, and cardiovascular disease . ATVB, 23, 1190-1196. [2003]

Kardia, S.L.R., Modell, S., Peyser, P.A. . Family-centered approaches to understanding and preventing coronary heart disease . American Journal of Preventive Medicine, 24, 143-151. [2003]

Kardia, S.L.R., Rozek, L.S., Krushkal, J., Ferrell, R.E., Turner, S.T., Hutchinson, R., Brown, A., Sing, C.F., Boerwinkle, E.B.. Genome-wide linkage analyses for hypertension genes in two ethnically and geographically diverse populations. American Journal Hyt, 16, 154-157. [2003]

Small, K.M., Wagoner, L.E., Levin, A.M., Kardia, S.L.R., Liggett, S.B. . Synergistic polymorphisms of ?1- and ?2C-adrenergic receptors and the risk of congestive heart failure . New England Journal Medicine, 347, 1135-1142. [2002]